Preheat oven to 450˚F.
In a large mixing bowl combine the flour, baking powder, baking soda, salt and pepper and whisk to combine. Using a fork or a pastry cutter, cut the cold butter into the flour mixture until crumbly. Make a well in the center, place pancetta and cheese in the well and pour buttermilk over. Carefully and slowly stir until it comes together and makes dough.
Turn the dough out onto lightly floured surface and, with floured hands, give it a quick knead 3-4 times to bring it together.
Pat the dough into a 8x8 square about 1-inch thick, and cut into 9 square biscuits.
Place on a baking sheet lined with parchment or a silpat, brush with melted butter, sprinkle with salt and pepper and place in hot oven till puffed up and golden brown, around 15-18 minutes.
Slice each biscuit in half and serve with sliced cheese, prosciutto, scrambled eggs and whatever else you want on the best breakfast sandwich!